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ypqP [2018-02-05T06:08:58.000Z]
C-terminal part of the split gene spsM (together with [gene|F42B27D5D7F3F39828940E377ABCC0730B25EA88|yodU]), spore envelope polysaccharide biosynthesis, in B. subtilis 168 the gene is disrupted by the SP-beta prophage
function
spore envelope polysaccharide biosynthesis
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.6|Miscellaneous metabolic pathways] → [category|SW 2.6.6.8|Biosynthesis of legionaminic acid (for spore crust))][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.5|Newly identified sporulation proteins (based on transcription profiling)]Gene
Coordinates
2,286,448 → 2,287,053
The protein
Paralogous protein(s)
[protein|5DB168A3D087AAEB003D7548A1A4356ABD07F712|EpsC] (for SpsM)[SW|Domains]
SpsM: Polysacc_synt_2 domain (Pfam accession number, PF02719) in the 18–296-aa region [Pubmed|25299644][SW|Localization]
cell membrane (according to Swiss-Prot)Expression and Regulation
Operons
genes
[gene|6CBEACD5C9C88319C4F9BE4C53F5C6534EF9135F|sprA]-[gene|240CD6EA3793821F5109252BDEF69C0120E454EF|ypqP]
description
[pubmed|22383849]sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [pubmed|22383849], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]view in new tabgenes
[gene|240CD6EA3793821F5109252BDEF69C0120E454EF|ypqP]
description
[pubmed|22383849]
view in new tabBiological materials
Mutant
MGNA-A061 (ypqP::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/61 NBRP B. subtilis, Japan]BKE21670 (Δ[gene|240CD6EA3793821F5109252BDEF69C0120E454EF|ypqP]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE21670 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AGATACAGCTTTATCTGTTT, downstream forward: _UP4_TAAAAACAAGCCTGTCTATCBKK21670 (Δ[gene|240CD6EA3793821F5109252BDEF69C0120E454EF|ypqP]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK21670 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AGATACAGCTTTATCTGTTT, downstream forward: _UP4_TAAAAACAAGCCTGTCTATCReferences
25299644,25326298,28535266